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Long range molecular dynamics study of regulation of eukaryotic glucosamine-6-phosphate synthase activity by UDP-GlcNAc

Glucosamine-6-phosphate (GlcN-6-P) synthase catalyses the first and practically irreversible step in hexosamine metabolism. The final product of this pathway, uridine 5’ diphospho N-acetyl-D-glucosamine (UDP-GlcNAc), is an essential substrate for assembly of bacterial and fungal cell walls. Moreover...

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Detalles Bibliográficos
Autores principales: Miszkiel, Aleksandra, Wojciechowski, Marek, Milewski, Sławomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224219/
https://www.ncbi.nlm.nih.gov/pubmed/21360186
http://dx.doi.org/10.1007/s00894-011-1003-x