Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

Down syndrome (DS) is the most frequent genetic disorder leading to intellectual disabilities and is caused by three copies of human chromosome 21. Mouse models are widely used to better understand the physiopathology in DS or to test new therapeutic approaches. The older and the most widely used mo...

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Detalles Bibliográficos
Autores principales: Duchon, Arnaud, Raveau, Matthieu, Chevalier, Claire, Nalesso, Valérie, Sharp, Andrew J., Herault, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224224/
https://www.ncbi.nlm.nih.gov/pubmed/21953411
http://dx.doi.org/10.1007/s00335-011-9356-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224224/
https://www.ncbi.nlm.nih.gov/pubmed/21953411
http://dx.doi.org/10.1007/s00335-011-9356-0

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