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A suicide gene approach using the human pro-apoptotic protein tBid inhibits HIV-1 replication

BACKGROUND: Regulated expression of suicide genes is a powerful tool to eliminate specific subsets of cells and will find widespread usage in both basic and applied science. A promising example is the specific elimination of human immunodeficiency virus type 1 (HIV-1) infected cells by LTR-driven su...

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Detalles Bibliográficos
Autores principales: Huelsmann, Peter M, Hofmann, Andreas D, Knoepfel, Stefanie A, Popp, Jasmin, Rauch, Pia, Di Giallonardo, Francesca, Danke, Christina, Gueckel, Eva, Schambach, Axel, Wolff, Horst, Metzner, Karin J, Berens, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224247/
https://www.ncbi.nlm.nih.gov/pubmed/21223573
http://dx.doi.org/10.1186/1472-6750-11-4