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Comparative void-volume analysis of psychrophilic and mesophilic enzymes: Structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility

BACKGROUND: Psychrophiles, cold-adapted organisms, have adapted to live at low temperatures by using a variety of mechanisms. Their enzymes are active at cold temperatures by being structurally more flexible than mesophilic enzymes. Even though, there are some indications of the possible structural...

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Detalles Bibliográficos
Autores principales: Paredes, Diana I, Watters, Kyle, Pitman, Derek J, Bystroff, Christopher, Dordick, Jonathan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224250/
https://www.ncbi.nlm.nih.gov/pubmed/22013889
http://dx.doi.org/10.1186/1472-6807-11-42