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Computational modelling elucidates the mechanism of ciliary regulation in health and disease

BACKGROUND: Ciliary dysfunction leads to a number of human pathologies, including primary ciliary dyskinesia, nephronophthisis, situs inversus pathology or infertility. The mechanism of cilia beating regulation is complex and despite extensive experimental characterization remains poorly understood....

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Detalles Bibliográficos
Autores principales: Kotov, Nikolay V, Bates, Declan G, Gizatullina, Antonina N, Gilaziev, Bulat, Khairullin, Rustem N, Chen, Michael ZQ, Drozdov, Ignat, Umezawa, Yoshinori, Hundhausen, Christian, Aleksandrov, Alexey, Yan, Xing-gang, Spurgeon, Sarah K, Smales, C Mark, Valeyev, Najl V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224258/
https://www.ncbi.nlm.nih.gov/pubmed/21920041
http://dx.doi.org/10.1186/1752-0509-5-143