A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells

BACKGROUND: Hypoxia-inducible factor-1 (HIF-1) is a master regulator of the transcriptional response to hypoxia. It is essential for angiogenesis and is associated with tumor progression and overexpression of HIF-1α has been demonstrated in many common human cancers. Therefore, HIF-1α is one of the...

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Detalles Bibliográficos
Autores principales: Manohar, Sonal M, Padgaonkar, Amol A, Jalota-Badhwar, Archana, Sonawane, Vinay, Rathos, Maggie J, Kumar, Sanjay, Joshi, Kalpana S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224262/
https://www.ncbi.nlm.nih.gov/pubmed/21819554
http://dx.doi.org/10.1186/1471-2407-11-338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224262/
https://www.ncbi.nlm.nih.gov/pubmed/21819554
http://dx.doi.org/10.1186/1471-2407-11-338

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