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Computer Aided Prediction of Biological Activity Spectra: Study of Correlation between Predicted and Observed Activities for Coumarin-4-Acetic Acids

Coumarin-4-acetic acids have been synthesized from various phenols and citric acid under Pechmann cyclisation conditions. All the compounds have been evaluated for antiinflammatory and analgesic activity in acute models. Compounds have also been evaluated for their ulcerogenic potential. Using the c...

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Detalles Bibliográficos
Autores principales: Basanagouda, M., Jadhav, V. B., Kulkarni, M. V., Rao, R. Nagendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224418/
https://www.ncbi.nlm.nih.gov/pubmed/22131629
http://dx.doi.org/10.4103/0250-474X.89764