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Nanometric self-assembling peptide layers maintain adult hepatocyte phenotype in sandwich cultures

BACKGROUND: Isolated hepatocytes removed from their microenvironment soon lose their hepatospecific functions when cultured. Normally hepatocytes are commonly maintained under limited culture medium supply as well as scaffold thickness. Thus, the cells are forced into metabolic stress that degenerat...

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Detalles Bibliográficos
Autores principales: Wu, Jonathan, Marí-Buyé, Núria, Muiños, Teresa Fernández, Borrós, Salvador, Favia, Pietro, Semino, Carlos E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224541/
https://www.ncbi.nlm.nih.gov/pubmed/21143997
http://dx.doi.org/10.1186/1477-3155-8-29