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Nanometric self-assembling peptide layers maintain adult hepatocyte phenotype in sandwich cultures
BACKGROUND: Isolated hepatocytes removed from their microenvironment soon lose their hepatospecific functions when cultured. Normally hepatocytes are commonly maintained under limited culture medium supply as well as scaffold thickness. Thus, the cells are forced into metabolic stress that degenerat...
Autores principales: | Wu, Jonathan, Marí-Buyé, Núria, Muiños, Teresa Fernández, Borrós, Salvador, Favia, Pietro, Semino, Carlos E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224541/ https://www.ncbi.nlm.nih.gov/pubmed/21143997 http://dx.doi.org/10.1186/1477-3155-8-29 |
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