On-chip constructive cell-network study (II): on-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network

BACKGROUNDS: Conventional in vitro approach using human ether-a-go-go related gene (hERG) assay has been considered worldwide as the first screening assay for cardiac repolarization safety. However, it does not always oredict the potential QT prolongation risk or pro-arrhythmic risk correctly. For a...

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Detalles Bibliográficos
Autores principales: Nomura, Fumimasa, Kaneko, Tomoyuki, Hattori, Akihiro, Yasuda, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224544/
https://www.ncbi.nlm.nih.gov/pubmed/21929750
http://dx.doi.org/10.1186/1477-3155-9-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224544/
https://www.ncbi.nlm.nih.gov/pubmed/21929750
http://dx.doi.org/10.1186/1477-3155-9-39

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