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Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing

BACKGROUND: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorithms, each justified by theory, simulation, or ad hoc validation and yet differing in practical results from equally justi...

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Detalles Bibliográficos
Autores principales: Yanofsky, Corey M, Bickel, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224549/
https://www.ncbi.nlm.nih.gov/pubmed/20109217
http://dx.doi.org/10.1186/1471-2105-11-63