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Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
BACKGROUND: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorithms, each justified by theory, simulation, or ad hoc validation and yet differing in practical results from equally justi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224549/ https://www.ncbi.nlm.nih.gov/pubmed/20109217 http://dx.doi.org/10.1186/1471-2105-11-63 |