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Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor
BACKGROUND: Streptomyces coelicolor, a model organism of antibiotic producing bacteria, has one of the largest genomes of the bacterial kingdom, including 7825 predicted protein coding genes. A large number of these genes, nearly 34%, are functionally orphan (hypothetical proteins with unknown funct...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224560/ https://www.ncbi.nlm.nih.gov/pubmed/21899768 http://dx.doi.org/10.1186/1756-0500-4-325 |