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A model-based circular binary segmentation algorithm for the analysis of array CGH data
BACKGROUND: Circular Binary Segmentation (CBS) is a permutation-based algorithm for array Comparative Genomic Hybridization (aCGH) data analysis. CBS accurately segments data by detecting change-points using a maximal-t test; but extensive computational burden is involved for evaluating the signific...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224564/ https://www.ncbi.nlm.nih.gov/pubmed/21985277 http://dx.doi.org/10.1186/1756-0500-4-394 |