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Predicting Bevirimat resistance of HIV-1 from genotype

BACKGROUND: Maturation inhibitors are a new class of antiretroviral drugs. Bevirimat (BVM) was the first substance in this class of inhibitors entering clinical trials. While the inhibitory function of BVM is well established, the molecular mechanisms of action and resistance are not well understood...

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Detalles Bibliográficos
Autores principales: Heider, Dominik, Verheyen, Jens, Hoffmann, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224585/
https://www.ncbi.nlm.nih.gov/pubmed/20089140
http://dx.doi.org/10.1186/1471-2105-11-37