Cargando…

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

BACKGROUND: The correlation between neurofibrillary tangles of tau and disease progression in the brains of Alzheimer's disease (AD) patients remains an area of contention. Innovative data are emerging from biochemical, cell-based and transgenic mouse studies that suggest that tau oligomers, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasagna-Reeves, Cristian A, Castillo-Carranza, Diana L, Sengupta, Urmi, Clos, Audra L, Jackson, George R, Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224595/
https://www.ncbi.nlm.nih.gov/pubmed/21645391
http://dx.doi.org/10.1186/1750-1326-6-39