Cargando…
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
BACKGROUND: The correlation between neurofibrillary tangles of tau and disease progression in the brains of Alzheimer's disease (AD) patients remains an area of contention. Innovative data are emerging from biochemical, cell-based and transgenic mouse studies that suggest that tau oligomers, a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224595/ https://www.ncbi.nlm.nih.gov/pubmed/21645391 http://dx.doi.org/10.1186/1750-1326-6-39 |