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Putative role of the adenosine A(3) receptor in the antiproliferative action of N(6)-(2-isopentenyl)adenosine
We tested a panel of naturally occurring nucleosides for their affinity towards adenosine receptors. Both N (6)-(2-isopentenyl)adenosine (IPA) and racemic zeatin riboside were shown to be selective human adenosine A(3) receptor (hA(3)R) ligands with affinities in the high nanomolar range (K (i) valu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224645/ https://www.ncbi.nlm.nih.gov/pubmed/21720785 http://dx.doi.org/10.1007/s11302-011-9244-9 |