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Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation

BACKGROUND: Radix ophiopogonis polysaccharide (ROP) has been found to be effective against myocardial ischemia. One of main problems with its use is its short in-vivo half-life, which makes the development of an effective delivery system necessary. To achieve better therapeutic effects and patient c...

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Detalles Bibliográficos
Autores principales: Lin, Xiao, Wang, Zhuo-Jun, Huang, Fang, Liang, Shuang, Shen, Lan, Feng, Yi, Ruan, Ke-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224713/
https://www.ncbi.nlm.nih.gov/pubmed/22131832
http://dx.doi.org/10.2147/IJN.S26306