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Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation
BACKGROUND: Radix ophiopogonis polysaccharide (ROP) has been found to be effective against myocardial ischemia. One of main problems with its use is its short in-vivo half-life, which makes the development of an effective delivery system necessary. To achieve better therapeutic effects and patient c...
Autores principales: | Lin, Xiao, Wang, Zhuo-Jun, Huang, Fang, Liang, Shuang, Shen, Lan, Feng, Yi, Ruan, Ke-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224713/ https://www.ncbi.nlm.nih.gov/pubmed/22131832 http://dx.doi.org/10.2147/IJN.S26306 |
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