Translesion DNA synthesis in the context of cancer research

During cell division, replication of the genomic DNA is performed by high-fidelity DNA polymerases but these error-free enzymes can not synthesize across damaged DNA. Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avo...

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Detalles Bibliográficos
Autores principales: Knobel, Philip A, Marti, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224763/
https://www.ncbi.nlm.nih.gov/pubmed/22047021
http://dx.doi.org/10.1186/1475-2867-11-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224763/
https://www.ncbi.nlm.nih.gov/pubmed/22047021
http://dx.doi.org/10.1186/1475-2867-11-39

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