Cargando…

Translesion DNA synthesis in the context of cancer research

During cell division, replication of the genomic DNA is performed by high-fidelity DNA polymerases but these error-free enzymes can not synthesize across damaged DNA. Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knobel, Philip A, Marti, Thomas M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224763/ https://www.ncbi.nlm.nih.gov/pubmed/22047021 http://dx.doi.org/10.1186/1475-2867-11-39

Ejemplares similares

Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases
por: Zhao, Linlin, et al.
Publicado: (2017)

Recent Advances in Understanding the Structures of Translesion Synthesis DNA Polymerases
por: Ling, Justin A., et al.
Publicado: (2022)

Multiple Strategies for Translesion Synthesis in Bacteria
por: Ippoliti, Paul J., et al.
Publicado: (2012)

Translesion DNA Polymerases and Cancer
por: Makridakis, Nick M., et al.
Publicado: (2012)

Protein–Protein Interactions in Translesion Synthesis
por: Dash, Radha Charan, et al.
Publicado: (2021)

DNA Polymerase β Gap-Filling Translesion DNA Synthesis
por: Chary, Parvathi, et al.
Publicado: (2012)

Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis
por: Saito, Yuichiro, et al.
Publicado: (2015)

Post-translesion synthesis repair
por: Jansen, Jacob G., et al.
Publicado: (2015)

Translesion Synthesis Polymerases in the Prevention and Promotion of Carcinogenesis
por: Stallons, L. Jay, et al.
Publicado: (2010)

The Role of PCNA Posttranslational Modifications in Translesion Synthesis
por: Shaheen, Montaser, et al.
Publicado: (2010)

The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
por: Gallina, Irene, et al.
Publicado: (2021)

Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases
por: Baruch-Torres, Noe, et al.
Publicado: (2017)

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells
por: Hendel, Ayal, et al.
Publicado: (2011)

Translesion-synthesis DNA polymerases participate in replication of the telomeres in Streptomyces
por: Tsai, Hsiu-Hui, et al.
Publicado: (2012)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
por: Hirota, Kouji, et al.
Publicado: (2016)

Translesion Synthesis of 2′-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases
por: Basu, Ashis K., et al.
Publicado: (2016)

Parkin regulates translesion DNA synthesis in response to UV radiation
por: Zhu, Xuefei, et al.
Publicado: (2017)

Direct visualization of translesion DNA synthesis polymerase IV at the replisome
por: Tuan, Pham Minh, et al.
Publicado: (2022)

Detection of endogenous translesion DNA synthesis in single mammalian cells
por: Egger, Tom, et al.
Publicado: (2023)

Structure of Monoubiquitinated PCNA and Implications for Translesion Synthesis and DNA Polymerase Exchange
por: Freudenthal, Bret D., et al.
Publicado: (2010)

Translesion synthesis of apurinic/apyrimidic siteanalogues by Y-family DNA polymerase Dbh from Sulfolobus acidocaldarius : Translesion synthesis of apurinic/apyrimidic site analogues
por: Wang, Weiwei, et al.
Publicado: (2022)

Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases
por: Ho, The Vinh, et al.
Publicado: (2011)

RNA-splicing factor SART3 regulates translesion DNA synthesis
por: Huang, Min, et al.
Publicado: (2018)

Protocol to analyze endogenous translesion DNA synthesis in single mammalian cells
por: Egger, Tom, et al.
Publicado: (2023)

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion
por: Hedglin, Mark, et al.
Publicado: (2016)

Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents
por: Choi, Jung-Suk, et al.
Publicado: (2017)

Structure and Mechanism of B-family DNA Polymerase ζ Specialized for Translesion DNA Synthesis
por: Malik, Radhika, et al.
Publicado: (2020)

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis
por: Jansen, Jacob G., et al.
Publicado: (2005)

Visualizing mutagenic repair: novel insights into bacterial translesion synthesis
por: Joseph, Asha Mary, et al.
Publicado: (2020)

Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress
por: Maiorano, Domenico, et al.
Publicado: (2021)

Architecture of Y-Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies
por: Chandani, Sushil, et al.
Publicado: (2010)

The Transcription Factor TFII-I Promotes DNA Translesion Synthesis and Genomic Stability
por: Fattah, Farjana J., et al.
Publicado: (2014)

Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin
por: Ziv, Omer, et al.
Publicado: (2014)

Translesion Synthesis in Plants: Ultraviolet Resistance and Beyond
por: Sakamoto, Ayako N.
Publicado: (2019)

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ
por: Yamanaka, Kinrin, et al.
Publicado: (2012)

Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions
por: Tsaalbi-Shtylik, Anastasia, et al.
Publicado: (2015)

Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis
por: Zhao, Gengjing, et al.
Publicado: (2017)

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery
por: Tonzi, Peter, et al.
Publicado: (2018)

Characterisation of the spectrum and genetic dependence of collateral mutations induced by translesion DNA synthesis
por: Póti, Ádám, et al.
Publicado: (2022)

Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity
por: Zhong, Xuejun, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_sii22nl58q9tn0ufoohh45b0cn