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Absence of association between pyronaridine in vitro responses and polymorphisms in genes involved in quinoline resistance in Plasmodium falciparum

BACKGROUND: The aim of the present work was to assess the in vitro cross-resistance of pyronaridine with other quinoline drugs, artesunate and several other commonly used anti-malarials and to evaluate whether decreased susceptibility to pyronaridine could be associated with genetic polymorphisms in...

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Detalles Bibliográficos
Autores principales: Pradines, Bruno, Briolant, Sébastien, Henry, Maud, Oeuvray, Claude, Baret, Eric, Amalvict, Rémy, Didillon, Eric, Rogier, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224917/
https://www.ncbi.nlm.nih.gov/pubmed/21108786
http://dx.doi.org/10.1186/1475-2875-9-339