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The ancient function of RB-E2F Pathway: insights from its evolutionary history

BACKGROUND: The RB-E2F pathway is conserved in most eukaryotic lineages, including animals and plants. E2F and RB family proteins perform crucial functions in cycle controlling, differentiation, development and apoptosis. However, there are two kinds of E2Fs (repressive E2Fs and active E2Fs) and thr...

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Detalles Bibliográficos
Autores principales: Cao, Lihuan, Peng, Bo, Yao, Lei, Zhang, Xinming, Sun, Kuan, Yang, Xianmei, Yu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224931/
https://www.ncbi.nlm.nih.gov/pubmed/20849664
http://dx.doi.org/10.1186/1745-6150-5-55