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Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

BACKGROUND: The integrase (IN) of human immunodeficiency virus type 1 (HIV-1) has been implicated in different steps during viral replication, including nuclear import of the viral pre-integration complex. The exact mechanisms underlying the nuclear import of IN and especially the question of whethe...

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Detalles Bibliográficos
Autores principales: Levin, Aviad, Armon-Omer, Ayelet, Rosenbluh, Joseph, Melamed-Book, Naomi, Graessmann, Adolf, Waigmann, Elisabeth, Loyter, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224947/
https://www.ncbi.nlm.nih.gov/pubmed/19961612
http://dx.doi.org/10.1186/1742-4690-6-112