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Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells

BACKGROUND: Human retinal pigment epithelial cells are promising target sites for small interfering RNA (siRNA) that might be used for the prevention and/or treatment of choroidal neovascularization by inhibiting the expression of angiogenic factor; for example, by downregulating expression of the v...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Wei, Lu, Da-Wen, Yeh, Ming-Kung, Shiau, Chia-Yang, Chiang, Chiao-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225218/
https://www.ncbi.nlm.nih.gov/pubmed/22128247
http://dx.doi.org/10.2147/IJN.S24447