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Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells
BACKGROUND: Human retinal pigment epithelial cells are promising target sites for small interfering RNA (siRNA) that might be used for the prevention and/or treatment of choroidal neovascularization by inhibiting the expression of angiogenic factor; for example, by downregulating expression of the v...
Autores principales: | Chen, Cheng-Wei, Lu, Da-Wen, Yeh, Ming-Kung, Shiau, Chia-Yang, Chiang, Chiao-Hsi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225218/ https://www.ncbi.nlm.nih.gov/pubmed/22128247 http://dx.doi.org/10.2147/IJN.S24447 |
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