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Age-related decrease of miRNA-92a levels in human CD8(+ )T-cells correlates with a reduction of naïve T lymphocytes

MicroRNA (miR)-17-92a expression plays a crucial role in lymphocyte ontogeny. We therefore set out to determine miR-92a expression levels in peripheral blood lymphocytes from healthy subjects to ascertain any association between these levels and ageing. We found a positive correlation between the mi...

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Detalles Bibliográficos
Autores principales: Ohyashiki, Michiyo, Ohyashiki, Junko H, Hirota, Ayako, Kobayashi, Chiaki, Ohyashiki, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225295/
https://www.ncbi.nlm.nih.gov/pubmed/22082184
http://dx.doi.org/10.1186/1742-4933-8-11