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Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

BACKGROUND: Prognostic and predictive significance of epidermal growth factor receptor (EGFR) in colorectal carcinomas (CRCs) is still controversial. The aim of the present study was to explore and correlate membrane and nuclear EGFR and cyclin-D1 protein expression with EGFR gene status of tumor ce...

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Detalles Bibliográficos
Autores principales: Dekanić, Andrea, Dobrila Dintinjan, Renata, Budisavljević, Ivana, Pećanić, Sanja, Žuvić Butorac, Marta, Jonjić, Nives
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225321/
https://www.ncbi.nlm.nih.gov/pubmed/22050898
http://dx.doi.org/10.1186/1746-1596-6-108