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TmDOTA-Tetraglycinate Encapsulated Liposomes as pH-Sensitive LipoCEST Agents

Lanthanide DOTA-tetraglycinate (LnDOTA-(gly)(4) (−)) complexes contain four magnetically equivalent amide protons that exchange with protons of bulk water. The rate of this base catalyzed exchange process has been measured using chemical exchange saturation transfer (CEST) NMR techniques as a functi...

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Detalles Bibliográficos
Autores principales: Opina, Ana Christina L., Ghaghada, Ketan B., Zhao, Piyu, Kiefer, Garry, Annapragada, Ananth, Sherry, A. Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225356/
https://www.ncbi.nlm.nih.gov/pubmed/22140438
http://dx.doi.org/10.1371/journal.pone.0027370