Acute Pancreatitis Accelerates Initiation and Progression to Pancreatic Cancer in Mice Expressing Oncogenic Kras in the Nestin Cell Lineage

Targeting of oncogenic Kras to the pancreatic Nestin-expressing embryonic progenitor cells and subsequently to the adult acinar compartment and Nestin-expressing cells is sufficient for the development of low grade pancreatic intraepithelial neoplasia (PanIN) between 2 and 4 months. The mice die aro...

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Detalles Bibliográficos
Autores principales: Carrière, Catherine, Young, Alison L., Gunn, Jason R., Longnecker, Daniel S., Korc, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225359/
https://www.ncbi.nlm.nih.gov/pubmed/22140463
http://dx.doi.org/10.1371/journal.pone.0027725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225359/
https://www.ncbi.nlm.nih.gov/pubmed/22140463
http://dx.doi.org/10.1371/journal.pone.0027725

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