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TRAF6 and IRF7 Control HIV Replication in Macrophages

The innate immune system recognizes virus infection and evokes antiviral responses which include producing type I interferons (IFNs). The induction of IFN provides a crucial mechanism of antiviral defense by upregulating interferon-stimulated genes (ISGs) that restrict viral replication. ISGs inhibi...

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Detalles Bibliográficos
Autores principales: Sirois, Mélissa, Robitaille, Lynda, Allary, Robin, Shah, Mohak, Woelk, Christopher H., Estaquier, Jérôme, Corbeil, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225375/
https://www.ncbi.nlm.nih.gov/pubmed/22140520
http://dx.doi.org/10.1371/journal.pone.0028125