Phosphodiesterase-5 Inhibition Mimics Intermittent Reoxygenation and Improves Cardioprotection in the Hypoxic Myocardium

Although chronic hypoxia is a claimed myocardial risk factor reducing tolerance to ischemia/reperfusion (I/R), intermittent reoxygenation has beneficial effects and enhances heart tolerance to I/R. Aim of the study: To test the hypothesis that, by mimicking intermittent reoxygenation, selective inhi...

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Detalles Bibliográficos
Autores principales: Milano, Giuseppina, Bianciardi, Paola, Rochemont, Viviane, Vassalli, Giuseppe, von Segesser, Ludwig K., Corno, Antonio F., Guazzi, Marco, Samaja, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225385/
https://www.ncbi.nlm.nih.gov/pubmed/22140481
http://dx.doi.org/10.1371/journal.pone.0027910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225385/
https://www.ncbi.nlm.nih.gov/pubmed/22140481
http://dx.doi.org/10.1371/journal.pone.0027910

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