Preparation and Characterization of a Lovastatin-Loaded Protein-Free Nanostructured Lipid Carrier Resembling High-Density Lipoprotein and Evaluation of its Targeting to Foam Cells

This study was designed to investigate whether a non-protein nanostructured lipid carrier (NLC) resembling high-density lipoprotein (HDL) could deliver a hydrophobic anti-atherogenic drug, lovastatin, to foam cells. Lovastatin-loaded NLC (LT-NLC) was prepared by a nanoprecipitation/solvent diffusion...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Xiao, Zhang, Wenli, Liu, Jianping, Shaw, John P., Shen, Yuanjun, Xu, Yiming, Lu, Hui, Wu, Zimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225525/
https://www.ncbi.nlm.nih.gov/pubmed/21927961
http://dx.doi.org/10.1208/s12249-011-9668-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225525/
https://www.ncbi.nlm.nih.gov/pubmed/21927961
http://dx.doi.org/10.1208/s12249-011-9668-0

Ejemplares similares