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Preparation and Characterization of a Lovastatin-Loaded Protein-Free Nanostructured Lipid Carrier Resembling High-Density Lipoprotein and Evaluation of its Targeting to Foam Cells

This study was designed to investigate whether a non-protein nanostructured lipid carrier (NLC) resembling high-density lipoprotein (HDL) could deliver a hydrophobic anti-atherogenic drug, lovastatin, to foam cells. Lovastatin-loaded NLC (LT-NLC) was prepared by a nanoprecipitation/solvent diffusion...

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Detalles Bibliográficos
Autores principales:	Gu, Xiao, Zhang, Wenli, Liu, Jianping, Shaw, John P., Shen, Yuanjun, Xu, Yiming, Lu, Hui, Wu, Zimei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225525/ https://www.ncbi.nlm.nih.gov/pubmed/21927961 http://dx.doi.org/10.1208/s12249-011-9668-0

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