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Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein
Loss of FMR1 gene function results in fragile X syndrome (FXS), the most common heritable form of intellectual disability. The protein encoded from this locus (FMRP) is an RNA binding protein thought to primarily act as a translational regulator, however recent studies implicate FMRP in other mechan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225737/ https://www.ncbi.nlm.nih.gov/pubmed/22037499 http://dx.doi.org/10.1038/nn.2950 |