Cargando…
Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein
Loss of FMR1 gene function results in fragile X syndrome (FXS), the most common heritable form of intellectual disability. The protein encoded from this locus (FMRP) is an RNA binding protein thought to primarily act as a translational regulator, however recent studies implicate FMRP in other mechan...
Autores principales: | Bhogal, Balpreet, Jepson, James E., Savva, Yiannis A., Pepper, Anita S.-R., Reenan, Robert A., Jongens, Thomas A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225737/ https://www.ncbi.nlm.nih.gov/pubmed/22037499 http://dx.doi.org/10.1038/nn.2950 |
Ejemplares similares
-
Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR
por: Marcucci, Roberto, et al.
Publicado: (2009) -
Argonaute2 Suppresses Drosophila Fragile X Expression Preventing Neurogenesis and Oogenesis Defects
por: Pepper, Anita S.-R., et al.
Publicado: (2009) -
Expression of concern on ‘Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR’
Publicado: (2023) -
The ADAR protein family
por: Savva, Yiannis A, et al.
Publicado: (2012) -
A molecular, phylogenetic and functional study of the dADAR mRNA truncated isoform during Drosophila embryonic development reveals an editing-independent function
por: Ghosh, Sushmita, et al.
Publicado: (2013)