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Detecting variable (V), diversity (D) and joining (J) gene segment recombination using a two-colour fluorescence system
BACKGROUND: Diversity of immunoglobulins and the T cell antigen receptors is achieved via the recombination activating gene (RAG)-mediated rearrangement of variable (V), diversity (D) and joining (J) gene segments, and this underpins the efficient recognition of a seemingly limitless array of antige...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225881/ https://www.ncbi.nlm.nih.gov/pubmed/20226006 http://dx.doi.org/10.1186/1759-8753-1-9 |