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Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

Reactive astrocytosis develops in many neurologic diseases including epilepsy. Astrocytotic contributions to pathophysiology are poorly understood. Studies examining this are confounded by comorbidities accompanying reactive astrocytosis. We found that high-titer AAV-eGFP astrocyte transduction indu...

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Detalles Bibliográficos
Autores principales: Ortinski, Pavel I., Dong, Jinghui, Mungenast, Alison, Yue, Cuiyong, Takano, Hajime, Watson, Deborah J., Haydon, Philip G., Coulter, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225960/
https://www.ncbi.nlm.nih.gov/pubmed/20418874
http://dx.doi.org/10.1038/nn.2535