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Selective induction of astrocytic gliosis generates deficits in neuronal inhibition
Reactive astrocytosis develops in many neurologic diseases including epilepsy. Astrocytotic contributions to pathophysiology are poorly understood. Studies examining this are confounded by comorbidities accompanying reactive astrocytosis. We found that high-titer AAV-eGFP astrocyte transduction indu...
Autores principales: | Ortinski, Pavel I., Dong, Jinghui, Mungenast, Alison, Yue, Cuiyong, Takano, Hajime, Watson, Deborah J., Haydon, Philip G., Coulter, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225960/ https://www.ncbi.nlm.nih.gov/pubmed/20418874 http://dx.doi.org/10.1038/nn.2535 |
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