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New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated)

It has been hypothesized that the protein C pathway is a pivotal link between the inflammation and coagulation cascades. The demonstration that a survival benefit is associated with administration of drotrecogin alfa (activated) (recombinant human activated protein C [APC]) in severe sepsis patients...

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Detalles Bibliográficos
Autores principales: Macias, William L, Yan, S Betty, Williams, Mark D, Um, Suzane L, Sandusky, George E, Ballard, Darryl W, Planquois, Jean-Michel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226161/
https://www.ncbi.nlm.nih.gov/pubmed/16168074
http://dx.doi.org/10.1186/cc3747