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New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated)
It has been hypothesized that the protein C pathway is a pivotal link between the inflammation and coagulation cascades. The demonstration that a survival benefit is associated with administration of drotrecogin alfa (activated) (recombinant human activated protein C [APC]) in severe sepsis patients...
Autores principales: | Macias, William L, Yan, S Betty, Williams, Mark D, Um, Suzane L, Sandusky, George E, Ballard, Darryl W, Planquois, Jean-Michel S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226161/ https://www.ncbi.nlm.nih.gov/pubmed/16168074 http://dx.doi.org/10.1186/cc3747 |
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