Cargando…

Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation

In goats, the PIS (polled intersex syndrome) mutation is responsible for both the absence of horns in males and females and sex-reversal affecting exclusively XX individuals. The mode of inheritance is dominant for the polled trait and recessive for sex-reversal. In XX PIS(-/- )mutants, the expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pailhoux, Eric, Vigier, Bernard, Schibler, Laurent, Cribiu, Edmond P, Cotinot, Corinne, Vaiman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226265/
https://www.ncbi.nlm.nih.gov/pubmed/15601595
http://dx.doi.org/10.1186/1297-9686-37-S1-S55