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For debate: substituting placebo controls in long-term Alzheimer's prevention trials

INTRODUCTION: Novel compounds with potential to attenuate or stop the progression of Alzheimer's disease (AD) from its presymptomatic stage to dementia are being tested in man. The study design commonly used is the long-term randomized, placebo-controlled trial (RPCT), meaning that many patient...

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Detalles Bibliográficos
Autores principales: Spiegel, René, Berres, Manfred, Miserez, André R, Monsch, Andreas U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226271/
https://www.ncbi.nlm.nih.gov/pubmed/21418632
http://dx.doi.org/10.1186/alzrt68