Cargando…

CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques

INTRODUCTION: APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and CR1 involved in Aβ clearance, and PICALM affecting intracellular trafficking. METHODS: We investigated the associations of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kok, Eloise H, Luoto, Teemu, Haikonen, Satu, Goebeler, Sirkka, Haapasalo, Hannu, Karhunen, Pekka J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226274/
https://www.ncbi.nlm.nih.gov/pubmed/21466683
http://dx.doi.org/10.1186/alzrt71