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CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques
INTRODUCTION: APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and CR1 involved in Aβ clearance, and PICALM affecting intracellular trafficking. METHODS: We investigated the associations of...
Autores principales: | Kok, Eloise H, Luoto, Teemu, Haikonen, Satu, Goebeler, Sirkka, Haapasalo, Hannu, Karhunen, Pekka J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226274/ https://www.ncbi.nlm.nih.gov/pubmed/21466683 http://dx.doi.org/10.1186/alzrt71 |
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