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Constitutive G(s )activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice

INTRODUCTION: The controlled expression of many genes, including G-protein coupled receptors (GPCRs), is important for delineating gene functions in complex model systems. Binary systems for inducible regulation of transgene expression are widely used in mice. One system is the tTA/TRE expression sy...

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Detalles Bibliográficos
Autores principales: Hsiao, Edward C, Nguyen, Trieu D, Ng, Jennifer K, Scott, Mark J, Chang, Wei Chun, Zahed, Hengameh, Conklin, Bruce R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226282/
https://www.ncbi.nlm.nih.gov/pubmed/21375737
http://dx.doi.org/10.1186/scrt52