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Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment

The vast majority of hematopoietic stem cells (HSCs) reside in specialized niches within the bone marrow during steady state, maintaining lifelong blood cell production. A small number of HSCs normally traffic throughout the body; however, exogenous stimuli can enhance their release from the niche a...

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Detalles Bibliográficos
Autores principales: Hoggatt, Jonathan, Pelus, Louis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226284/
https://www.ncbi.nlm.nih.gov/pubmed/21418553
http://dx.doi.org/10.1186/scrt54