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Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid

INTRODUCTION: Local synthesis of interferon within B16 tumors mediates anti-tumor effects. Based on reports that stem cells are recruited to tumors, and because systemic administration of interferon causes dose-limiting undesirable side effects, we wanted to improve the anti-tumor effects of interfe...

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Detalles Bibliográficos
Autores principales: Krause, Christopher D, Izotova, Lara S, Ren, Gwangwen, Yuan, Zeng-Rong, Shi, Yufang, Chen, Chiann-Chyi, Ron, Yacov, Pestka, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226286/
https://www.ncbi.nlm.nih.gov/pubmed/21401924
http://dx.doi.org/10.1186/scrt56