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Generation of recombinant single-chain antibodies neutralizing the cytolytic activity of vaginolysin, the main virulence factor of Gardnerella vaginalis

BACKGROUND: Gardnerella vaginalis is identified as the predominant colonist of the vaginal tract in women with bacterial vaginosis. Vaginolysin (VLY) is a protein toxin released by G. vaginalis. VLY possesses cytolytic activity and is considered as a main virulence factor of G. vaginalis. Inhibition...

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Detalles Bibliográficos
Autores principales: Pleckaityte, Milda, Mistiniene, Edita, Lasickiene, Rita, Zvirblis, Gintautas, Zvirbliene, Aurelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226441/
https://www.ncbi.nlm.nih.gov/pubmed/22047084
http://dx.doi.org/10.1186/1472-6750-11-100