Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules

BACKGROUND: Myotonic dystrophy type 1 (DM1) is the most common muscle dystrophy in adults. The disease is caused by a triplet expansion in the 3'end of the myotonic dystrophy protein kinase (DMPK) gene. In order to develop a human cell model for investigation of possible effects of antisense an...

Descripción completa

Detalles Bibliográficos
Autores principales: Larsen, Jan, Pettersson, Olof J, Jakobsen, Maria, Thomsen, Rune, Pedersen, Christina B, Hertz, Jens M, Gregersen, Niels, Corydon, Thomas J, Jensen, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226528/
https://www.ncbi.nlm.nih.gov/pubmed/22078098
http://dx.doi.org/10.1186/1756-0500-4-490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226528/
https://www.ncbi.nlm.nih.gov/pubmed/22078098
http://dx.doi.org/10.1186/1756-0500-4-490

Ejemplares similares